We invite passionate and knowledgeable individuals to join us at One Healthy Reason, the premier health conference focused on urban social determinants of health. This groundbreaking event aims to bring together experts, researchers, policymakers, and stakeholders from diverse fields to address the social factors that influence health outcomes in urban populations. Together, we will explore evidence-based strategies, foster collaboration, and develop effective solutions to improve the health and well-being of individuals living in urban areas.